Chemistry and Bioactivity of NeoMTA Plus™ versus MTA Angelus® Root Repair


The aim of this study is to analyze the chemistry and bioactivity of NeoMTA Plus in comparison with the conventional root repair materials.


Unhydrated and hydrated (initial and final sets) materials were analyzed by Fourier transform infrared(FTIR) spectroscopy and X-ray diffraction (XRD). For bioactivity study, small holes of dentin discs were filled with either materials, immersed in PBS for 15 days, and analyzed with FTIR and scanning electron microscope with energy dispersive X-ray(SEM/EDX). The calculation of crystallinity and carbonate/phosphate (CO3/PO4) ratio of surface precipitates (from FTIR) and calcium/phosphate (Ca/P) ratio (from EDX) was statistically analyzed using t-test or ANOVA, respectively, at 0.05 significance.


Both materials are tricalcium silicate-based that finally react to be calcium silicate hydrate. NeoMTA Plus has relatively high aluminium and sulfur content, with tantalum oxide as an opacifier instead of zirconium oxide in MTA Angelus. NeoMTAPlus showed better apatite formation, higher crystallinity and Ca/P but lower CO3/PO4ratio than MTA Angelus. SEM showed globular structure with a small particle size in NeoMTA Plus while spherical structure with large particle size in MTA Angelus.


Due to fast setting, higher crystallinity, and better bioactivity of NeoMTA Plus, it can be used as a pulp and root repair material.

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